Viable Alternative for Diagnosing Coronary Artery Disease on the Horizon

 

According to a new study published in the New England Journal of Medicine, Cardiac Computed Tomography (CT) can potentially provide a safer alternative to coronary angiography for assessing patients who suffer from stable chest pain or have undiagnosed Coronary Artery Disease (CAD).

Researchers used a randomized trial to conclude that more than 3,500 patients with stable chest pain in a randomized trial had a lower risk of major procedure-related complications with the use of CT. In contrast, initial cardiac CT and coronary angiography had similar cardiovascular risks.

Marc Dewey, MD, head of the Department of Radiology on Campus Charite Mitte, said, “The trial confirmed that the CT-based examination is safe in patients with stable chest pain and suspected coronary artery disease. Among the patients referred for cardiac catheterization and included in this trial, the risk of major cardiovascular events was found to be similar in both the CT and catheterization groups, occurring in 2.1% and 3.0% of patients, respectively. The incidence of major, procedure-related complications was found to be lower in patients managed with an initial CT strategy.”

The study was conducted between October 3, 2015, to April 12, 2019, by 26 European medical centers and involved 3,667 patients who were randomized in a 1:1 ratio to undergo CT or invasive coronary angiography.

Patients eligible for the study were required to be over 30 years old and referred due to stable chest pain with a high probability of obstructive CAD.

The study’s primary outcome focus was on major adverse cardiovascular events, some of which include cardiovascular death, nonfatal MI, or nonfatal stroke. Secondary procedure-related complications that took place either during or within the first 48 hours after CT invasive coronary angiography were also of interest.

A total of 90 major adverse cardiovascular events occurred among the study participants during the follow-up period.

Henryk Dreger, Deputy Head of Charite’s Department of Cardiology and Angiology said, “Now that it has been standardized and quality tested as part of the trial, this method could be made more widely available as part of the routine clinical care of people with intermediate CAD risk.”

RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

 

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

Safely Using Linear Accelerators in Cancer Treatment

 

Linear accelerators are now widely used in treating a variety of cancers. A linear accelerator delivers directed X-rays or electrons to a tumor, destroying cancer cells while ensuring that surrounding tissue is protected. However, this type of radiation still poses risks, so how do manufacturers and operators ensure the safety of patients and operators?

All companies that manufacture linear accelerators have a strict quality control process. Systems are built to confirm that the machine will not deliver a higher dose than that prescribed by the radiation oncologist. Additionally, safety measures are designed into the linear accelerator that ensures it is impossible to turn the machine on without all the treatment conditions being met.

When a linear accelerator is installed, strict requirements must be met for the area it is situated in. For the operational staff's safety, it is installed in a room lined with lead and concrete, and the controls for turning it on/off are situated outside of this room. Since the machine only emits radiation when turned on, this almost entirely eliminates the risk of accidental exposure.

At the start of each day and before any patient is treated, the radiation therapist makes sure that the linear accelerator is working correctly and performs checks for uniformity of the radiation intensity across the beam. In addition, a medical physicist conducts more detailed monthly and annual checks.

Another essential part of maintaining safety is keeping good records of patient exposure to the linear accelerator. All medical facilities using linear accelerators to treat cancer will ensure their staff are adequately trained and kept updated on the latest guidance on their use and safe limits for patient exposure. Reference: https://www.radiologyinfo.org/en/info/linac#bf774c98e5ab4192886da7fd06714070

 

RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

Novel ‘Cure’ For Cancer Treatment

 

A new report published in Nature titled “Decade-long leukemia remissions with persistence of CD4+ CAR T cells” highlights a novel treatment called CAR T, which is being hailed as a “cure” for cancer by Dr. Carl June, the principal investigator for the trial at the University of Pennsylvania.

June said, “Now we can finally say the word ‘cure’ with CAR T cells.” In 2010, when the trial began, the idea for this sort of therapy “was way out there,” he added.

June and his colleagues reported that the CAR T therapy wiped out cancer in two out of the three initial early-trial patients, all of whom had chronic lymphocytic leukemia. Though the cancer disappeared, the CAR T cells stayed circulating through patients’ bloodstreams, almost guarding the body against future attacks.

In CAR T therapy, T cells (white blood cells that fight viruses) are removed from a patient’s blood and re-introduced after being genetically engineered to fight cancer. Patients’ T cells are taught to recognize and destroy B cells, a key player in cancer formation throughout the body. Without B cells – or cancer – patients require regularly-scheduled infusions of immunoglobulin infusions, which replenish antibodies.

Many people with blood cancer have benefitted from CAR T therapy, which has proved especially effective against acute leukemia. Roughly a third of patients who underwent the CAR T therapy have gone into remission, but many patients later relapse.

Dr. John F. DiPersio, chief of the division of oncology at Washington University in St. Louis, said, “The question is not only why some patients relapse or are resistant to therapy but why are some patients cured?”

He continued, “Oncologists don’t use words like ‘cure’ lightly or easily or, frankly, very often,” he said. “I guarantee that it’s not being used lightly. The patients we treated had far advanced disease,” he noted, adding, “the biggest disappointment is that it doesn’t work all the time.”

RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

 

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

Henry Ford Health System Implants Novel Therapy for Brain Tumors

 

Surgeons at Michigan’s Henry Ford Health System successfully treated a patient who suffers from a recurrent brain tumor by delivering a dose of radiation therapy directly on the tumor. This new approach could revolutionize treatment by delaying or preventing future tumor cells from regrowing. Called GammaTile Therapy, the surgically targeted radiation therapy was the first of its kind performed in Michigan; the patient was a 41-year-old male.

Adam Robin, M.D., a neurosurgeon at the Hermelin Brain Tumor Center at Henry Ford, said, “The current standard of care for brain tumors is tumor resection, often followed by radiation, chemotherapy, or a combination of both. Approximately half of patients treated for brain tumors experience tumor recurrence within a year. In his most recent surgery, the patient was treated with a form of surgically targeted radiation therapy, which targets residual tumor cells with radiation before they can significantly replicate. Our hope is this therapy will delay or prevent the tumor cells from replicating and forming a recurrent tumor.”

GammaTile Therapy is cleared by the FDA and designed to delay tumor regrowth while protecting healthy brain tissue in patients who suffer from recurring tumors.

Mira M. Shah, M.D., a radiation oncologist at Henry Ford, external beam radiation therapy is usually delivered no sooner than two- to three weeks after surgery to let the incision heal. With GammaTile, the radiation is focused on specific areas of the brain using a type of brachytherapy (internal radiation) which delivers a therapeutic dose to the tumor during surgery.

Leaving the healthy tissue unharmed, GammaTile maximizes the amount of radiation aimed at the tumor and is critical for those patients who have received external beam radiation therapy, which exposes healthy tissue to radiation.

A bioresorbable, conformable 3D-collaten tile uses uniformly spaced radiation sources to target the tumor cavity after the tumor is removed. In just 33 days, 90 percent of the radiation dose is delivered, and after 100 days, the GammaTiles are considered free from radiation. The placement of GammaTile takes approximately five minutes.

RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

 

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

Using AI for Lung Disease Diagnosis

 

Lung cancer is the leading cause of cancer-related deaths globally. Five-year survival rates are at roughly 20 percent, according to Cancer.net. Those who smoke cigarettes have the highest risk for disease, along with nonsmokers who are exposed to toxins like arsenic, radon, asbestos, radiation, air pollution, and more.

Artificial Intelligence (AI) has been introduced to help diagnose the presence of lung cancer. Imaging is critical to lung cancer care; with help from AI, lung cancer can potentially be spotted sooner.

A new study combines CT information with clinical data to precisely forecast lung cancer. The AI considers factors such as nodule size, age, years smoked, cancer history, occupational exposure, and more.

More than four million people worldwide die prematurely due to a severe respiratory illness each year. Long-term exposure to dangerous toxins, particles, gases, or harsh temperatures can significantly affect the lungs. Certain occupations are more at risk than others, such as those who work as steelworkers, miners, or with textiles and automobiles.

Chronic Obstructive Pulmonary Disease (COPD) is a life-threatening illness causing emphysema. In clinical settings, emphysema is assessed by patient history, lung function, radiographs, and more. However, these tools are not able to make a diagnosis of mild emphysema. AI radiography is the most effective tool to detect issues that might normally slip under the radar.

A study released in October outlines how AI could match professional radiologists to predict emphysema in patients.

RadParts is the world’s largest independent distributor of OEM replacement parts. We specialize in low-cost parts for repairing linear accelerator and radiation equipment. Our mission is to provide high-quality, user-friendly, low-cost parts and support for linear accelerators and radiation equipment. Contact RadParts at 877-704-3838 or visit us on the web: https://www.radparts.com.

 

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.